Tuberculosis population is infected with tuberculosis. According to

(TB) is still the major cause of concern among the infectious diseases. The
bacterium responsible for causing TB is Mycobacterium
tuberculosis (M. tb). The disease transmits by the respiratory route in the
form of aerosol droplets containing the pathogen released by the infected
patients while coughing or sneezing. Pathogen main target is the lung but it
also has the ability to affect the various other parts of body, which may
include bones, brain, stomach, intestine and various other organs of the body. World’s
one-third population is infected with tuberculosis. According to the WHO (World
health organization) report 2015, 1.8 million people died from the disease out
of the total 10.4 million who got ill with this malady. Nearly 10% of the
children got affected with this disease in the year 2015. Co-infection of TB in
HIV (Human immunodeficiency virus)-positive patients is the prime cause of
death among these individuals. In the year 2015, 35% of the deaths among the
HIV positive people were due to TB. To reach the goal of the ‘End TB strategy’,
aiming to reduce TB deaths by 90% and incidence by 80% by 2030 we need a
comprehensive approach for the treatment, diagnosis and vaccination of the
disease. An estimate by WHO report 2017 claimed that South-East Asia region
accounts for nearly 45.6% of the total TB incidence. Members of SEAR namely the
Democratic People?s Republic Korea, Indonesia, Myanmar, Bangladesh, India and
Thailand are among the global list of 30 high-TB-burden countries. One third of
the world burden is shared by both India (23%) and Indonesia (10%). India ranks
number six in terms of incidence rate and mortality rate. Despite several
advances being made to eliminate TB, this disease is still creating havoc
because of an upsurge in the cases of extensively drug-resistant TB (XDR-TB)
and Multi drug-resistant TB (MDR-TB). Out of the total cases of MDR-TB only 52%
patients were treated successfully worldwide. 49% of MDR-TB cases from SEAR
were cured. In the year 2015, Drug resistant TB claimed 250000 lives globally.
In 2015 worldwide cases of MDR-TB represented only 37% of the estimated 340000
MDR/RR-TB cases among pulmonary TB patients. 200000 cases of MDR/RR-TB
(Rifampicin resistant) were reported from SAE region out of which alone India
had 130000 incidence of MDR/RR-TB. 11% of all new TB cases globally were
accounted by HIV positive people in 2015 while 4.7% (227000) cases were
reported from SAE region. 74000 people died from HIV associated TB from the SAE
region in the year 2015



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